MFF, inc, nc, TV-parody A1 Chloe and Zoe - by Chloe - Starts out as to naughty girls you chose their ageand the story has two endings that you choose from, a non-consensual rape ending or a science-fictional with Wild West ending. She becomes impregnated and has the baby on the ship as source of entertainment. She is tortured, raped, humiliated and abused MF-teens, nc, rp A Bad Reaction - by Vulgus - A young single mother and her young teenage daughter are victimized by mom's parole officer after she is wrongly convited of a crime.
Viruses are acellular bioactive parasites that attack virtually every form of cellular life. Their shape is either pseudospherical with icosahedral symmetry, as in the poliomyelitis virus, or rodlike, as in the tobacco mosaic virus TMV.
A virus surrounded only by protein coat capsid is a naked virus; some viruses e. Hepatitis G HGV [ 59 ] viral loads in symptomatic patients are 0. Thus the typical blood particle burdens in viremia are much the same as in bacteremia, roughly 0.
Viral infections can be very difficult to eradicate pharmaceutically, as most treatments are virustatic, not virucidal. Disseminated systemic candidiasis is effectively managed with 0.
Respiratory fungal histoplasmosis Histoplasma capulatum may be treated with oral doses of itraconazole at 0. Blood parasites typically have a juvenile form that is ovoid or ring-shaped with dimensions of microns, and an adult tubular form measuring microns in width and microns in length [ 68 ].
In Trypanosoma brucei, the number of trypanosomes in blood fluctuates in waves, and the organisms are typically undetectable for 3 out of 5 days [ 69 ]. Trypomastigotes have an I. Trypanosoma brucei gambiense inoculated into mice has an LD50 of 0.
Malaria may be treated with several oral doses of chloroquine phosphate totalling 2. The infection is characterized by repetitive cycles of bloodborne organisms, or rickettsemia.
However, most of these parasites are found in the red cells, and the organism's appearance in the blood plasma is incidental to its activity. Plasma titers for free R. Microbivore Scaling Analysis and Baseline Design The foregoing review suggests that existing treatments for many septicemic agents often require large quantities of medications that must be applied over long periods of time, and often achieve only incomplete eradication, or merely growth arrest, of the pathogen.
A nanorobotic device that could safely provide quick and complete eradication of bloodborne pathogens using relatively low doses of devices would be a welcome addition to the physician's therapeutic armamentarium.
The following analysis assumes a bacterial target e. The microbivore is an oblate spheroidal nanomedical device consisting of billion precisely arranged structural atoms plus another billion mostly gas or water molecules when fully loaded Section 3.
The nanorobot measures 3. Its gross geometric volume of The device may consume up to pW of continuous power while in operation and can completely digest trapped microbes at a maximum throughput of 2 micron3 per second cycle, large enough to internalize almost all relevant microbes in a single gulp.
As in previous designs [ 2 ], to help ensure high reliability the system presented here has tenfold redundancy in all major components, excluding only the largest passive structural elements. During each cycle of operation, the target bacterium is bound to the surface of the microbivore via species-specific reversible binding sites [ 1 ].
Telescoping robotic grapples emerge from silos in the device surface, establish secure anchorage to the microbe's plasma membrane, then transport the pathogen to the ingestion port at the front of the device where the cell is internalized into a morcellation chamber.
After sufficient mechanical mincing, the morcellated remains are pistoned into a digestion chamber where a preprogrammed sequence of engineered enzymes are successively injected and extracted, reducing the morcellate primarily to monoresidue amino acids, mononucleotides, glycerol, free fatty acids and simple sugars, which are then harmlessly discharged into the environment through an exhaust port at the rear of the device, completing the cycle.
This "digest and discharge" protocol [ 1 ] is conceptually similar to the internalization and digestion process practiced by natural phagocytes, but the artificial process should be much faster and cleaner. For example, it is well-known that macrophages release biologically active compounds such as muramyl peptides during bacteriophagy [ 76 ], whereas well-designed microbivores need only release biologically inactive effluent.
Introduction to the nano Text Editor. Once you've logged into your linux ssh account, you'll need to use a text editor to write your code. There are a few already installed on the system (vi, emacs, etc.), but these have a bit of a learning curve associated with them. The sand in the hourglass continues to run out. Can populations be awakened in time to make a difference? In so many ways the answer to that question depends on what we collectively do, or don’t. 10 Reasons Why You Should Participate in NaNoWriMo. So if you choose to use NaNo to write your first draft, know that the work you do this November will suck. Why? if you take the time to pre-write your NaNo project before November rolls around, you'll set yourself up for a successful first draft. You see, the more time you put into.
The microbivore digestive system has four fundamental components -- an array of reversible binding sites to initially bind and trap target microbes Section 3. A collision between a bacterium of the target species and the nanorobotic device brings their surfaces into intimate contact, allowing reversible binding sites on the microbivore hull to recognize and weakly bind to the bacterium.10 Reasons Why You Should Participate in NaNoWriMo.
So if you choose to use NaNo to write your first draft, know that the work you do this November will suck. Why? if you take the time to pre-write your NaNo project before November rolls around, you'll set yourself up for a successful first draft.
You see, the more time you put into. Writers: Don’t do NaNoWriMo.
Please. Don’t do it. Date: 16 Oct Author: You don’t need NaNo.
Write your book according to your rules, your rhythms, what works for you. It won’t be easy, but nothing worth doing ever is.
Frankly, 50k it works out to around half an hour of writing a day for me. Then usually I spend another. Nano may be years in the making, as even the most successful coins today had to prove their systems.
But in this case, adoption has been extremely rapid, supported by the broad community. In this case, the early and wide distribution of RAI Blocks created an instant community.
The term "nano-technology" was first used by Norio Atomic force microscope tips can be used as a nanoscale "write head" to deposit a chemical upon a surface in a desired pattern in a process for example, feature-oriented scanning approach, atoms or molecules can be moved around on a surface with scanning probe microscopy techniques.
The concepts that seeded nanotechnology were first discussed in by renowned physicist Richard Feynman in his talk There's Plenty of Room at the Bottom, in which he described the possibility of synthesis via direct manipulation of barnweddingvt.com term "nano-technology" was first used by Norio Taniguchi in , though it was not widely known.
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